Oct 5, 2013

New Kind of Microscope Uses Neutrons

Researchers at MIT, working with partners at NASA, have developed a new concept for a microscope that would use neutrons -- subatomic particles with no electrical charge -- instead of beams of light or electrons to create high-resolution images.

Among other features, neutron-based instruments have the ability to probe inside metal objects -- such as fuel cells, batteries, and engines, even when in use -- to learn details of their internal structure. Neutron instruments are also uniquely sensitive to magnetic properties and to lighter elements that are important in biological materials.

The new concept has been outlined in a series of research papers this year, including one published this week in Nature Communications by MIT postdoc Dazhi Liu, research scientist Boris Khaykovich, professor David Moncton, and four others.

Moncton, an adjunct professor of physics and director of MIT's Nuclear Reactor Laboratory, says that Khaykovich first proposed the idea of adapting a 60-year-old concept for a way of focusing X-rays using mirrors to the challenge of building a high-performing neutron microscope. Until now, most neutron instruments have been akin to pinhole cameras: crude imaging systems that simply let light through a tiny opening. Without efficient optical components, such devices produce weak images with poor resolution.

Beyond the pinhole

"For neutrons, there have been no high-quality focusing devices," Moncton says. "Essentially all of the neutron instruments developed over a half-century are effectively pinhole cameras." But with this new advance, he says, "We are turning the field of neutron imaging from the era of pinhole cameras to an era of genuine optics."

"The new mirror device acts like the image-forming lens of an optical microscope," Liu adds.

Because neutrons interact only minimally with matter, it's difficult to focus beams of them to create a telescope or microscope. But a basic concept was proposed, for X-rays, by Hans Wolter in 1952 and later developed, under the auspices of NASA, for telescopes such as the orbiting Chandra X-ray Observatory (which was designed and is managed by scientists at MIT). Neutron beams interact weakly, much like X-rays, and can be focused by a similar optical system.

It's well known that light can be reflected by normally nonreflective surfaces, so long as it strikes that surface at a shallow angle; this is the basic physics of a desert mirage. Using the same principle, mirrors with certain coatings can reflect neutrons at shallow angles.

A sharper, smaller device

The actual instrument uses several reflective cylinders nested one inside the other, so as to increase the surface area available for reflection. The resulting device could improve the performance of existing neutron imaging systems by a factor of about 50, the researchers say -- allowing for much sharper images, much smaller instruments, or both.

The team initially designed and optimized the concept digitally, then fabricated a small test instrument as a proof-of-principle and demonstrated its performance using a neutron beam facility at MIT's Nuclear Reactor Laboratory. Later work, requiring a different spectrum of neutron energies, was carried out at Oak Ridge National Laboratory (ORNL) and at the National Institute of Standards and Technology (NIST).

Such a new instrument could be used to observe and characterize many kinds of materials and biological samples; other nonimaging methods that exploit the scattering of neutrons might benefit as well. Because the neutron beams are relatively low-energy, they are "a much more sensitive scattering probe," Moncton says, for phenomena such as "how atoms or magnetic moments move in a material."

The researchers next plan to build an optimized neutron-microscopy system in collaboration with NIST, which already has a major neutron-beam research facility. This new instrument is expected to cost a few million dollars.

Read more at Science Daily

Once 'Extinct' Pinocchio Lizard Pokes His Nose Out

This ain't no lie: The Pinocchio lizard was thought to be extinct for 50 years, but has been rediscovered in the cloud forests of Ecuador.

After searching for the long-nosed animal for three years, a team of photographers and researchers found the lizard recently in a stretch of pristine cloud forest in the northwest part of the country, said Alejandro Arteaga, a co-founder of the educational and ecotourism company Tropical Herping, which conducted the search for the lizard.

Also called the Pinocchio anole (an anole is a type of lizard), the animal is named after a certain dishonest wooden puppet and was first discovered in 1953, Arteaga said. But wasn't seen between the 1960s and 2005, when an ornithologist saw one crossing a road in the same remote area in northwest Ecuador. This is only the third time scientists have spotted it since 2005, Arteaga added.

Scientists typically look for lizards at night when most of the animals sleep, and when their coloring becomes paler and they are less likely to scurry away, Arteaga told LiveScience's OurAmazingPlanet. One of his colleagues found a single male Pinocchio anole clinging to a branch over a stream in January. The team then kept it overnight before photographing it in the morning in its natural habitat.

"After looking for so long ... It was very thrilling to find this strange lizard," Arteaga said. The team then let the animal go.

Arteaga and his colleagues were searching for the Pinocchio anole because it was the last lizard they needed to complete their book, "The Amphibians and Reptiles of Mindo," a rural region a two-hour drive north of Quito, Ecuador's capital. The book was published this summer.

Pinocchio anoles (Anolis proboscis) are an endangered species and have been found in only four locations, mostly along a single stretch of road, according to the International Union for Conservation of Nature, a global environmental group. They have one of the smallest ranges of any lizard in the world, Arteaga said.

Read more at Discovery News

Oct 4, 2013

Sieving Through 'Junk' DNA Reveals Disease-Causing Genetic Mutations

Scientists have revealed nearly 100 genetic variants implicated in the development of cancers such as breast cancer and prostate cancer.

The new method designed by the team, described in the journal Science, identified these variants in the under-explored regions of DNA that do not code for proteins, but instead influence activity of other genes. As even more whole genome sequences become available, this approach can be applied to find any potential disease-causing variant in the non-coding regions of the genome.

Researchers can now identify DNA regions within non-coding DNA, the major part of the genome that is not translated into a protein, where mutations can cause diseases such as cancer.

Their approach reveals many potential genetic variants within non-coding DNA that drive the development of a variety of different cancers. This approach has great potential to find other disease-causing variants.

Unlike the coding region of the genome where our 23,000 protein-coding genes lie, the non-coding region -- which makes up 98% of our genome -- is poorly understood. Recent studies have emphasised the biological value of the non-coding regions, previously considered 'junk' DNA, in the regulation of proteins. This new information provides a starting point for researchers to sieve through the non-coding regions and identify the most functionally important regions.

"Our technique allows scientists to focus in on the most functionally important parts of the non-coding regions of the genome," says Professor Mark Gerstein, senior author from the University of Yale. "This is not just beneficial for cancer research, but can be extended to other genetic diseases too."

The team used the full set of genetic variants from the first phase of the 1000 Genomes Project, together with information about the non-coding regions generated by the ENCODE Project, and identified regions that did not accumulate much variation.

Protein-coding genes play a crucial role in human survival and fitness, and are under strong 'purifying' selection, which removes variation. The team found that some non-coding DNA regions showed almost the same low levels of variation as protein-coding genes, and called these 'ultrasensitive' regions.

Within the ultrasensitive regions, they looked at specific single DNA letters that, when altered, caused the greatest disturbance to the genetic region. If this non-coding, ultrasensitive region is central to a network of many related genes, variation can cause a greater knock-on effect, resulting in disease.

They integrated all this information to develop a computer workflow known as FunSeq. This system prioritises genetic variants in the non-coding regions based on their predicted impact on human disease.

"Our method is a practical and successful way to screen for purifying selection in non-coding regions of the genome using freely available data such as those from the ENCODE and 1000 Genomes Projects," says Dr Yali Xue, author from the Wellcome Trust Sanger Institute. "It really shows the value of these large-scale open access data-sets."

The team applied FunSeq to 90 cancer genomes including breast cancer, prostate cancer and brain tumours, and found nearly 100 potential non-coding cancer driving variants. In the breast cancer genomes, for example, they found a single DNA letter change that seems to have great impact on the development of breast cancer. This single letter change occurs in an ultrasensitive region that is central to a network of many related genes.

Read more at Science Daily

Giant Planet Seen Lurking Inside the Galactic Bulge

Astronomers have discovered a giant world orbiting a star using a quirk of Einstein’s general relativity. This “microlensing” event enabled astronomers to test a new survey technique to detect the alien world from over 25,000 light-years away, deep inside the Milky Way’s galactic bulge.

Microlensing events occur when a star passes in front of another more distant star. As the nearer star passes in front, its gravitational field — which is (according to general relativity) bending the surrounding spacetime — deflects the light from the more distant star. Like the lens in a magnifying glass, the starlight is magnified and Earth-bound observatories are able to spot a transient brightening. Information about the “lens” (the foreground star) and any planets in tow can then be deduced.

The microlensing event “MOA-2011-BLG-322″ was detected during a 2011 observing season of a collaboration of observatories. Astronomers of the Microlensing Observations in Astrophysics (MOA — New Zealand/Japan), Optical Gravitational Lensing Experiment (OGLE — Poland) and Wise (Israel) all reported the event. Of the 218 microlensing events detected during that season, only 80 were confirmed by all three networks. Of those 80, three showed signs of a clear “planetary anomaly.”

A planetary anomaly is caused by a secondary mass (i.e. a planet) creating its own spacetime warping, adding detail to the microlensed starlight. Microlensing has therefore become a useful tool in the search for exoplanets orbiting distant stars. This technique contrasts greatly with the two leading techniques of exoplanet detection — the “transit” technique (the dimming of starlight caused by an accompanying exoplanet passing in front) and the “radial velocity” technique (the wobble of a star caused by the gravitational tugging of an orbiting exoplanet).

Although exoplanets have been discovered via microlensing before, this is the first planetary detection that uses only high cadence survey data after the event. Usually, when a microlensing event is detected, alerts are sent out to collaborating astronomers who then slew their telescopes toward the event and measurements are taken. In the case of MOA-2011-BLG-322, only data from the three surveys were used to estimate the star’s mass and the nature of the planetary companion. According to the researchers, this “shows that the survey data alone can be sufficient to characterize a planetary model.”

The exoplanet detected in this case has a mass of approximately eight times that of Jupiter and its star is likely an M-type star, around one third the mass of our sun. The exoplanet has an orbital distance of nearly 4 astronomical units (AU); or four-times the Earth-sun distance. From this observation, some interesting science can be done.

It would appear that MOA-2011-BLG-322′s massive planet exists in an orbit beyond its host star’s “snowline”. This is a region around any given star where protoplanetary material in the protoplanetary disk of a young star begins to freeze, making it a ripe environment for planets to form. However, this world appears to be too massive for its comparatively close orbit.

“According to the core accretion scenario, Jovian planets form beyond the snowlines of their parent stars, but massive planets around M-type stars should be rare, since their formation times are longer than the typical disk lifetime,” the researchers write. “In the disk instability planet-formation scenario massive planets do form around M stars, but at distances of over 7 AU.”

For such a large planet to be orbiting only 4 AU from its parent star, there appears to be some conflicts with existing planetary formation theories. Fortunately, microlensing is highly sensitive to detecting worlds beyond the snowlines of their stars, so with further discoveries by microlensing surveys will come better knowledge of how massive planets form or migrate from wider orbits.

Read more at Discovery News

Engraved Penises Reveal Birth Date of Italian City

Two penises engraved on a 2,000 year old stone may shed light on the foundation of the city of Aosta in northern Italy, revealing its deep connection with the Roman emperor Augustus.

Named Augusta Praetoria Salassorum by the Romans -- who captured it from the local Salassi people in 25 B.C. to control strategic mountain passes -- Aosta boasts several monuments dedicated to Augustus.

"But the newly discovered stone tells even more about Aosta’s connection with the Roman emperor. It reveals the city was built under Augustus’ sign during the winter solstice," Giulio Magli, professor of archaeoastronomy at Milan's Polytechnic University, told Discovery News.

Found covered in mud at a depth of 5 feet during excavation work at one of the town’s towers, the elaborately carved stone is still walled up in its original position on the southeast corner of the monument, known as Balivi Tower.

"Originally, the stone stood in plain view. But in the early Middle Ages the tower was probably flooded and its basis covered by alluvial material," Stella Bertarione, the archaeologist who made the discovery, told Discovery News.

Bertarione works at the Superintendency for cultural heritage and activities of the Aosta Valley autonomous region.

Carved on both sides, the block features two very clear figures on one side -- a phallus and, over it, a spade -- and some partly damaged reliefs on the other. There, a phallus is again represented. Over it, a plough and a partly eroded character which appears to be a Capricorn.

The plough and the spade openly hint to the sulcus primigenius, the original trench plowed to mark the perimeter of a new city in the Roman foundation ceremony. Related to the god Priapus, the phallic effigies most likely had an “apotropaic” function, evoking some sort of protection from evil forces.

"The chunk of mud has certainly preserved the stone from damage and censorship," Bertarione said. "In medieval times the evident phallic figures would have been erased since they were regarded as obscene pagan symbols."

Located on the northeast corner of the Roman walls, the Balivi Tower stands in the highest point of the ancient city. Looking at the carved stone, Bertarione noticed a peculiarity.

"The tips of the two phalli point to southeast, where the sun raises in the winter months," she said.

In the analysis that followed, Magli examined the original urban plan taking into account the complex natural horizon of the Alps in which Aosta’s valley is nested.

The results confirmed Aosta’s orientation to the sun rising on the winter solstice.

"We can estimate that the foundation of Aosta began on Dec. 23. On that day, the sun raises right in the direction pointed by the phalli on the stone," Bertarione said.

Read more at Discovery News

'Gravity': Science vs. Fiction

How Real Is This Orbital Blockbuster?

Director Alfonso Cuarón's visually stunning film "Gravity," in theaters today, is already being heralded as one of the year's best movies. Sandra Bullock and George Clooney star as astronauts whose mission goes spectacularly wrong when a cloud of orbital debris shreds their shuttle, cuts off communication and leaves them stranded in space.

These details have already been revealed in the film's trailers, but what the previews can't convey is the impressive sense of authenticity and verisimilitude that director Cuarón brings to the big screen. Thanks to a brilliant visual design and strategic use of 3-D effects, the movie feels like being in space.

That sense of authenticity also applies to the film's depiction of the specifics of an actual NASA space mission. It's clear that the filmmakers did their homework. The movie is careful to stay within the realm of plausibility demanded by the genre of hard science fiction.

But just to be sure, we asked former NASA astronaut Leroy Chiao -- a veteran of three shuttle missions, four space walks and a six-month stint on the International Space Station -- to help us separate the science from the fiction. Warning: Several significant plot spoilers dead ahead.

Orbital Debris Causes … Complications

The crisis in the film is precipitated when the Russians blow up one of their own satellites, triggering a chain reaction that sends a cloud of lethal debris toward our heroes at around, oh, 17,000 mph. Chiao says the dangers of such a scenario are quite real and have been studied extensively.

"Just in recent history, the Chinese conducted an anti-weapons satellite test," Chiao says. "They blew up one of their old weather satellites, which created a bunch of debris."

Could such an incident really set off a chain-reaction that wipes out everything in orbit?

"It's not implausible, but it's unlikely," Chiao says. "Of course, if you have orbital debris, it can damage satellites or other spacecraft and potentially cause them to break up in turn. But the thing is, satellites are actually spaced pretty far apart. To get a cascade or chain reaction is pretty unlikely."

Houston ... We Have a Good One For You

Before everything goes haywire in orbit, the spacewalking astronauts Ryan Stone (Bullock) and Matt Kowalski (Clooney) keep it loose by casually chatting, joking with ground control in Houston and even listening to music. Is it really that casual up in space?

"Yeah, during spacewalks we're tied in with Houston and tied in with the crew inside (the shuttle), of course," Chiao says. "We have some light-hearted moments and we joke around a bit."

Can You Steal a Space Capsule?

When the debris cloud destroys the astronauts' ride back home -- that is to say, the space shuttle -- Stone is forced to improvise by breaking into an old Soyuz spacecraft docked at the International Space Station. Chiao says such orbital grand theft is quite possible, but pretty tricky.

"In order to open the outer door of the airlock you have to have the inner hatch closed and the air evacuated in between," Chaio says. "On the American airlock, you could open the pressure equalization valves, and there's a handle outside so you could definitely open the outer hatch. But the trick is, on the inside, the crew would have to have already closed that inner hatch. Otherwise you let all the air out of the station. If the crew configured it that way before they abandoned ship, then yes that could happen. It's physically possible."

Correct Use of Jargon is Critical

After the orbital debris cascade knocks out communication satellites, Stone and Kowalski lose contact with ground control. They keep transmitting, though, in hopes that someone is listening. Each message begins with the rather haunting phrase, "Transmitting in the blind..."

"Yeah, that's real phraseology and that's used in aircraft operations also," Chiao says. "You call 'in the blind' if you're not receiving them, but you think they might be receiving you. You're basically letting them know that you're not able to hear them."

Read more at Discovery News

Oct 3, 2013

New 'Bigfoot' Sighting Latest in Series of Hoaxes

A team of Bigfoot buffs called a press conference earlier this week to present what they called “definitive video and DNA evidence from the elusive Sasquatch.” Several short video clips, presented with more sincerity than credibility, turned out to be a publicity teaser for an upcoming Bigfoot movie.

Sharon Hill, a blogger who has written extensively about this story for Doubtful News.com, noted that “high definition footage of the creature known as ‘Matilda’ presented… This conference was announced via press release but honestly, those of us seriously following this fiasco assumed it would be another joke. And so it is. Not only does Matilda remarkably resemble a throw rug but the face seems eerily reminiscent of Chewbacca. The clips that were shown in the news conference were described as short and grainy. That’s kind of odd for HD footage, don’t you think?”

Pro-tip: If your high-def camera can’t distinguish between a sleeping Sasquatch and a throw rug, you need to buy lens cleaner. And why would there only be a few seconds of video? Surely the team stuck around long enough to videotape it as it woke up, if not call for additional cameras to surround it — or even a tranquilizer gun.

History of Bigfoot Hoaxes

This is only the latest of many confirmed and suspected Bigfoot hoaxes on film and video. The most famous recording of a Bigfoot is the short film taken in 1967 by Roger Patterson and Bob Gimlin.

Shot in Bluff Creek, Calif., it shows a supposed female Bigfoot striding through a clearing. The film is generally considered a hoax, though to this day — nearly 50 years later — it is widely described by Bigfoot believers to be by far the best evidence for the creature.

This is of course not the first time that people have claimed to have found a Bigfoot, live or dead. The head of a prominent Bigfoot group, Tom Biscardi, appeared on the “Coast to Coast with George Noory” radio show in 2005 claiming that his group had captured a Bigfoot. It was, he said, a male standing eight feet tall and weighing over 400 pounds. Despite repeated promises to make the amazing discovery public, the whole thing turned out to be a hoax designed to drum up publicity for a Bigfoot film.

Three years later two Georgia men claimed to have found a dead Bigfoot creature towering nearly eight feet all, covered with hair, and weighing 500 pounds. They released a photograph of it inside a freezer and promised follow-up video and genetic analysis. That DNA evidence never materialized because the “Bigfoot” ended up being a rubber costume.

The history of Bigfoot evidence is full of similar audacious, high-profile hoaxes, and indeed there is no category of Bigfoot evidence that has not been widely hoaxed, including video, photographs, tracks, hair samples, blood samples and DNA samples. (One well-known sample of “Bigfoot blood” turned out to be transmission fluid.)

Dozens of people have admitted hoaxing Bigfoot prints. These days it’s easier than ever to fake Bigfoot tracks; anyone in the world can buy a cast of an alleged Bigfoot on eBay and use it to make tracks that resemble those accepted by some “experts” as authentic.

These hoaxes frustrate those in the Bigfoot research community who take the subject seriously and try to bring science and good research to the mystery. Faked evidence — sometimes created by sincere Bigfoot believers — not only casts doubt on potentially legitimate evidence, but can also waste enormous amounts of time and effort in disproving the hoax.

In one case hoaxing turned deadly; last year a man in Montana died while trying to pull off a Bigfoot hoax. Randy Lee Tenley was struck and killed by several cars; according to police he was dressed in a dark camouflage costume standing near a highway at night in an attempt to spur Bigfoot sighting reports.

Read more at Discovery News

Jewish Prayer Book Predates Oldest Torah Scroll

Scholars are calling a rare Hebrew text dating back to the 9th century the earliest known Jewish prayer book, predating the world's oldest Torah scroll.

The 50-page book is 4.3 inches tall and about 4 inches wide and is written in an archaic form of Hebrew, on pages of aged parchment. The text includes 100 Jewish blessings and discusses topics such as the apocalyptic tale of the End Times and the Passover Seder.

Carbon testing dates the prayer book to the year 840, which is 300 to 400 years before the oldest known Torah scroll from the 12th and 13th centuries.

"This find is historical evidence supporting the very fulcrum of Jewish religious life," said Jerry Pattengale, executive director of the Green Scholars Initiative, the group that announced the find. "This Hebrew prayer book helps fill the gap between the Dead Sea Scrolls and other discoveries of Jewish texts from the ninth and tenth centuries."

"This was a liturgical set of prayers, hymns and poems used for various occasions," Pattengale told the Huffington Post. "The prayer book is really what most of the Jewish community would be in touch with on a daily basis, a connection between the Bible and their daily worship."

The book is the Jewish equivalent of an early complete edition of the Christian Book of Common Prayer.

Started by the Green family of the retail chain Hobby Lobby, the Green Scholar's Initiative is the research arm of The Green Collection, one of the world's largest private collections of biblical texts and artifacts containing more than 40,000 items.

Read more at Discovery News

Lake That Turns Animals to Stone? Not Quite

Lake Natron in Tanzania is one of the most serene lakes in Africa, but it's also the source of some of the most phantasmagorical photographs ever captured — images that look as though living animals had instantly turned to stone.

The alkaline water in Lake Natron has a pH as high as 10.5 and is so caustic it can burn the skin and eyes of animals that aren't adapted to it. The water's alkalinity comes from the sodium carbonate and other minerals that flow into the lake from the surrounding hills. And deposits of sodium carbonate — which was once used in Egyptian mummification — also acts as a fantastic type of preservative for those animals unlucky enough to die in the waters of Lake Natron.

Despite some media reports, the animal didn't simply turn to stone and die after coming into contact with the lake's water. In fact, Lake Natron's alkaline waters support a thriving ecosystem of salt marshes, freshwater wetlands, flamingos and other wetland birds, tilapia and the algae on which large flocks of flamingos feed. Now, photographer Nick Brandt has captured haunting images of the lake and its dead in a book titled "Across the Ravaged Land" (Abrams Books, 2013).

Brandt discovered the remains of flamingos and other animals with chalky sodium carbonate deposits outlining their bodies in sharp relief. "I unexpectedly found the creatures — all manner of birds and bats — washed up along the shoreline of Lake Natron," Brandt wrote in his book. "No one knows for certain exactly how they die, but … the water has an extremely high soda and salt content, so high that it would strip the ink off my Kodak film boxes within a few seconds."

"I took these creatures as I found them on the shoreline, and then placed them in 'living' positions, bringing them back to 'life,' as it were," Brandt wrote, referring to the way he repositioned the animals. "Reanimated, alive again in death."

During breeding season, more than 2 million lesser flamingos (Phoenicopterus minor) use the shallow lake as their primary breeding ground in Africa. The flamingos' nests are built on small islands that form in the lake during the dry season.

Lake Natron is one of two alkaline lakes in that area of East Africa; the other is Lake Bahi. Both are terminal lakes that do not drain out to any river or sea; they are fed by hot springs and small rivers. As shallow lakes in a hot climate, their water temperatures can reach as high as 106 degrees Fahrenheit (41 degrees Celsius).

Read more at Discovery News

Fake Scientific Paper Fools 157 Journals

A spoof scientific report was recently accepted for publication in 157 journals around the world, proving how flawed some open-access publications are.

The fake paper was part of a sting operation orchestrated by John Bohannon, a contributing news correspondent to the prestigious peer-reviewed journal Science.

He wrote the paper under the fake name “Ocorrafoo Cobange,” supposedly a biologist at the Wassee Institute of Medicine in Asmara. No such institute or biologist exists.

Bohannon, in an article in the latest issue of Science, describes the fake paper as follows:

“Molecule X from lichen species Y inhibits the growth of cancer cell Z. To substitute for those variables, I created a database of molecules, lichens, and cancer cell lines and wrote a computer program to generate hundreds of unique papers.”

That might sound reasonable enough, but the study was riddled with obvious errors and contradictions that an expert in the field should have caught immediately.

Bohannon took the sting operation one step further, by slightly changing each version of the paper before he sent it out to the various journals.

“Submitting identical papers to hundreds of journals would be asking for trouble,” he explained.

To switch up the affiliations, for example, he randomly combined Swahili words and African names with generic institutional words and African capital cities.

“My hope was that using developing world authors and institutions would arouse less suspicion if a curious editor were to find nothing about them on the Internet,” Bohannon wrote.

To position himself as a foreigner writing in his non-native language (the papers were all submitted in English), he translated the paper into French with Google Translate and then translated the result back into English, correcting the worst mistranslations.

To ensure that the versions of the paper “were both fatally flawed and credible submissions,” he had two independent groups of molecular biologists at Harvard University review the paper to fine-tune the scientific flaws so that, as Bohannon described, the mistakes “were both obvious and boringly bad.”

He then submitted the versions of the paper, at a rate of about 10 per week, to 304 peer-reviewed, open-access journals around the world. Despite the paper’s incredible flaws, 157 of the journals accepted it for publication. Only 36 of the journals solicited responded with substantive comments that recognized the report’s scientific problems.

What’s more, Bohannon discovered that some of the journals are not based in the countries they claim. Although many had American or European-sounding titles, several of these publications were actually based in India.

Read more at Discovery News