Showing posts with label Computer Simulations. Show all posts
Showing posts with label Computer Simulations. Show all posts

May 4, 2024

Astronomers' simulations support dark matter theory

Computer simulations by astronomers support the idea that dark matter -- matter that no one has yet directly detected but which many physicists think must be there to explain several aspects of the observable universe -- exists, according to the researchers, who include those at the University of California, Irvine.

The work addresses a fundamental debate in astrophysics -- does invisible dark matter need to exist to explain how the universe works the way it does, or can physicists explain how things work based solely on the matter we can directly observe? Currently, many physicists think something like dark matter must exist to explain the motions of stars and galaxies.

"Our paper shows how we can use real, observed relationships as a basis to test two different models to describe the universe," said Francisco Mercado, lead author and recent Ph.D. graduate from the UC Irvine Department of Physics & Astronomy who is now a postdoctoral scholar at Pomona College. "We put forth a powerful test to discriminate between the two models."

The test involved running computer simulations with both types of matter -- normal and dark -- to explain the presence of intriguing features measured in real galaxies. The team reported their results in Monthly Notices of the Royal Astronomy Society.

The features in galaxies the team found "are expected to appear in a universe with dark matter but would be difficult to explain in a universe without it," said Mercado. "We show that such features appear in observations of many real galaxies. If we take these data at face value, this reaffirms the position of the dark matter model as the one that best describes the universe we live in."

These features Mercado noted describe patterns in the motions of stars and gas in galaxies that seem to only be possible in a universe with dark matter.

"Observed galaxies seem to obey a tight relationship between the matter we see and the inferred dark matter we detect, so much so that some have suggested that what we call dark matter is really evidence that our theory of gravity is wrong," said co-author James Bullock, professor of physics at UCI and dean of the UCI School of Physical Sciences. "What we showed is that not only does dark matter predict the relationship, but for many galaxies it can explain what we see more naturally than modified gravity. I come away even more convinced that dark matter is the right model."

The features also appear in observations made by proponents of a dark matter-free universe. "The observations we examined -- the very observations where we found these features -- were conducted by adherents of dark matter-free theories," said co-author Jorge Moreno, associate professor of physics and astronomy at Pomona College. "Despite their obvious presence, little-to-no analysis was performed on these features by that community. It took folks like us, scientists working with both regular and dark matter, to start the conversation."

Moreno added that he expects debate within his research community to follow in the wake of the study, but that there may be room for common ground, as the team also found that such features only appear in their simulations when there is both dark matter and normal matter in the universe.

"As stars are born and die, they explode into supernovae, which can shape the centers of galaxies, naturally explaining the existence of these features," said Moreno. "Simply put, the features we examined in observations require both the existence of dark matter and the incorporation of normal-matter physics."

Now that the dark matter model of the universe appears to be the leading one, the next step, Mercado explained, is to see if it remains consistent across a dark matter universe.

Read more at Science Daily

Feb 28, 2022

Computer drug simulations offer warning about promising diabetes and cancer treatment

Using computer drug simulations, researchers have found that doctors need to be wary of prescribing a particular treatment for all types of cancer and patients.

The drug, called metformin, has traditionally been prescribed for diabetes but has been used in clinical settings as a cancer treatment in recent years.

The researchers say while metformin shows great promise, it also has negative consequences for some types of cancers.

"Metformin is a wonder drug, and we are just beginning to understand all its possible benefits," said Mehrshad Sadria, a PhD candidate in applied mathematics at the University of Waterloo. "Doctors need to examine the value of the drug on a case-by-case basis, because for some cancers and some patient profiles, it may actually have the opposite of the intended effect by protecting tumour cells against stress."

The computer-simulated treatments use models that replicate both the drug and the cancerous cells in a virtual environment. Such models can give clinical trials in humans a considerable head-start and can provide insights to medical practitioners that would take much longer to be discovered in the field.

"In clinical settings, drugs can sometimes be prescribed in a trial and error manner," said Anita Layton, professor of applied mathematics and Canada 150 Research Chair in mathematical biology and medicine at Waterloo. "Our mathematical models help accelerate clinical trials and remove some of the guesswork. What we see with this drug is that it can do a lot of good but needs more study."

The researchers say their work shows the importance of precision medicine when considering the use of metformin for cancer and other diseases. Precision medicine is an approach that assumes each patient requires individualized medical assessment and treatment.

"Diseases and treatments are complicated," Sadria said. "Everything about the patient matters, and even small differences can have a big impact on the effect of a drug, such as age, gender, genetic and epigenetic profiles. All these things are important and can affect a patient's drug outcome. In addition, no one drug works for everyone, so doctors need to take a close look at each patient when considering treatments like metformin."

Read more at Science Daily

Dec 27, 2021

Computer simulation models potential asteroid collisions

An asteroid impact can be enough to ruin anyone's day, but several small factors can make the difference between an out-of-this-world story and total annihilation. In AIP Advances, by AIP Publishing, a researcher from the National Institute of Natural Hazards in China developed a computer simulation of asteroid collisions to better understand these factors.

The computer simulation initially sought to replicate model asteroid strikes performed in a laboratory. After verifying the accuracy of the simulation, Duoxing Yang believes it could be used to predict the result of future asteroid impacts or to learn more about past impacts by studying their craters.

"From these models, we learn generally a destructive impact process, and its crater formation," said Yang. "And from crater morphologies, we could learn impact environment temperatures and its velocity."

Yang's simulation was built using the space-time conservation element and solution element method, designed by NASA and used by many universities and government agencies, to model shock waves and other acoustic problems.

The goal was to simulate a small rocky asteroid striking a larger metal asteroid at several thousand meters per second. Using his simulation, Yang was able to calculate the effects this would have on the metal asteroid, such as the size and shape of the crater.

The simulation results were compared against mock asteroid impacts created experimentally in a laboratory. The simulation held up against these experimental tests, which means the next step in the research is to use the simulation to generate more data that can't be produced in the laboratory.

This data is being created in preparation for NASA's Psyche mission, which aims to be the first spacecraft to explore an asteroid made entirely of metal. Unlike more familiar rocky asteroids, which are made of roughly the same materials as the Earth's crust, metal asteroids are made of materials found in the Earth's inner core. NASA believes studying such an asteroid can reveal more about the conditions found in the center of our own planet.

Yang believes computer simulation models can generalize his results to all metal asteroid impacts and, in the process, answer several existing questions about asteroid interactions.

Read more at Science Daily