Milk Drinkers Share Common Ancestor

Like a milk mustache that just won't go away, a shared genetic signature marks many Europeans and Indians as descendants from a common milk-drinking ancestor within the last 7,500 years.

The majority of Europeans and Indians who can drink milk share the mutation known as -13910T. Scientists already knew that the mutation was what allowed most European adults to drink milk.

“To our surprise we found that the -13910T mutation was also common in India – especially in those populations with a tradition of milk drinking,” said Toomas Kivisild of Cambridge University, senior author of the study, in a press release.

“Not only that, but by looking at nearby genetic regions we could show that the Indian -13910T has the same origin as that found in Europeans; that it could lead back to the same few people who may have migrated between Europe and India,” said Kivisild.

All human babies can drink milk because they produce an enzyme called lactase, which breaks down milk sugar or lactose. But only about a third of the world's adults can drink milk without suffering abdominal pain, bloating, nausea, diarrhea, and other symptoms of lactose intolerance.

The genetic mutation that allows adults to drink milk, called lactase persistence, seems to have evolved separately in Europe, Africa, and the Middle East. But until now, the source of lactase persistence in India, the world's largest drinker and producer of milk, was a mystery.

“India was an unknown quantity. But since lactase persistence had evolved independently in the Middle East and Africa, and because cattle had been domesticated independently in India around seven or eight thousand years ago, we were expecting to see uniquely Indian genetic causes,” said lead author, Cambridge’s Irene Gallego Romero.

As the advertisement says, milk does a body good. So good that the genetic mutation allowing milk drinking seemingly gave a survival advantage to lactose tolerant adults. The gene then spread through populations even if a large scale migration of milk drinkers didn't accompany the introduction of cattle.

“Genetic data doesn’t support some sort of large migration of people from Europe to India in the last 10,000 years. What’s more likely is that just a few migrants carried this mutation to India, and then it spread quickly,” said co-author Mark Thomas of University College London.

Read more at Discovery News